"Every art should become science, and every science should become art."
Friedrich von Schlegel
The Shnyrova Lab
Mechanisms of Cellular Membrane Remodeling
WHat we do
Fission and fusion by dynamins
It all begun some 2 billion years ago, when endosymbiosis changed forever the internal world of
eukaryotic cells. The sudden engulfment of bacteria, allowed the eukaryotic cells to have an alternative source
of energy, but another important evolution step took place through the symbiosis. This mostly overlooked
event was the birth of a new protein family, called dynamins, that took control over the dynamics of
the endomembrane systems in Eukaryotes. We want to understand how evolution of dynamins correlates with that of endomembrane systems.
Model Nanotemplates for studying membrane remodeling
We play with lipid membranes to mimic cellular games.